There's a similarly legendary quality to this exchange, which appears on the surface to be a performer dealing with a very drunk audience member who is making a lot of noise. Performer cuts down drunk with a fairly damning indictment of his wasted life that he "ain't done nothin' with" because he only loves whisky.
It's a harsh remark, with all the more force behind it for being delivered by the mighty Howlin' Wolf. What is really eyebrow raising if you're a nerdy blues cove, which I am, is that the object of the comment, the rowdy drunk, is Son House. And then the Wolf sings, which is always remarkable, regardless.